Enantioselective 1,4-addition of cyclopropylboronic acid catalyzed by rhodium/chiral diene complexes.
نویسندگان
چکیده
Rhodium-catalyzed asymmetric addition of cyclopropylboronic acids to electron-deficient alkenes such as alkenylsulfones, enones, enoates, and nitroalkenes proceeded to give high yields of the corresponding 1,4-addition products with high enantioselectivity.
منابع مشابه
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Asymmetric 1,4-addition reactions with nitroalkenes are valuable because the resulting chiral nitro compounds can be converted into various useful species often used as chiral building blocks in drug and natural product synthesis. In the present work, asymmetric 1,4-addition reactions of arylboronic acids with nitroalkenes catalyzed by a rhodium complex with a chiral diene bearing a tertiary bu...
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 40 شماره
صفحات -
تاریخ انتشار 2015